Rangan and team, I’d love to better understand the intricacies of cholesterol. If you have a high LDL but your VLDL and triglycerides are low, is it still a problem? What exactly is APO-B and how does that influence your risk of vascular disease? If cholesterol helps in the creation of vitamin D, how can someone with high cholesterol have a vitamin d deficiency? Is there a link between cholesterol and thyroid conditions? Are statins a miracle or not really all they are touted to be, as studies don’t always seem to show them as an effective broad solution. There is a lot of conflicting info on cholesterol and would value a deep dive on it!
Many people have atrial fibrillation. I've heard this can be helped by weight reduction. Presumably it can be prevented from happening in the first place, but can it be totally reversed by health interventions (nutrition, exercise etc) When 'heart disease' is specified with regard to lifestyle interventions - does this just mean 'cardiovascular heart conditions' or does it include conductive issues (eg atrial fibrillation)?
I thought this would be a good area to look into - I see various information on the web but can't really work out what is myth and what is evidence based. I know mouths and teeth are usually the domain of dentists rather than doctors, but being the start of the digestive tract, surely the mouth must be interconnected with all the other systems of the body. What is good mouth hygiene? Should we be using mouthwashes? On the one hand one component of mouthwash is said to destroy coronavirus (this statement is not fact checked!!) but on the other hand surely mouthwash has a bad effect on the mouth microbiome. I recently saw mouth probiotics for sale - how do these work if they are swallowed as pills? Are some toothpastes bad for the mouth microbiome (eg titanium dioxide components)? Does coconut oil mouth rinsing have any merit? Bad breath is common and has knock on effects socially Good teeth give people confidence to smile and has positive social effects Good saliva aids digestion. Chewing is important for jaw formation. Bad bacteria in the mouth easily track to other parts of the body - leading to heart problems, pneumonia etc Does brushing 2x per day do the cleaning job? Can eating an apple at the end of a meal do as good a job? There are lots of unanswered questions in this area Thank you - have recently found your podcasts and have been mega bingeing!! Have found lots of them so helpful.